Obydul Huq

Consultant Physiotherapist & Managing director Doctor’s Physiotherapy center, Bangladesh

Abstract Title: Advances and Challenges in Parkinson’s Disease: Integrating Multidisciplinary Insights for Therapeutic Innovation

Biography:

Dr. Obydul Huq has completed Bachelor of Physiotherapy from D Y Patil University, Pune, India. He also did PGT in Neuro Physiotherapy from Bangladesh. He is working 20 years in this field. Presently he is Managing director of Doctor`s Physiotherapy Centre in Dhaka, Bangladesh.

Research Interest:

Parkinson’s disease (PD), the second most prevalent neurodegenerative disorder, affects over 10 million globally, characterized by motor symptoms—tremors, rigidity, bradykinesia—and non-motor manifestations such as cognitive decline and autonomic dysfunction. Pathologically, PD involves the degeneration of dopaminergic neurons in the substantia nigra and the accumulation of α-synuclein aggregates within Lewy bodies, though emerging research implicates the gut-brain axis in disease propagation. Etiology is multifactorial, encompassing genetic mutations (e.g., LRRK2, SNCA), environmental exposures, and aging-related cellular dysfunction. Current therapies, primarily levodopa and deep brain stimulation, offer symptomatic relief but fail to halt progression. Recent advancements highlight promising disease-modifying strategies, including immunotherapies targeting α-synuclein, gene editing, and stem cell therapies. Innovations in neuroimaging and biomarker discovery enhance early diagnosis, while precision medicine approaches address clinical heterogeneity. Challenges persist in understanding pathogenic mechanisms, optimizing neuroprotection, and personalizing treatments.